The real-life couple will play opposite each other in three-part drama Stonehouse, retelling the bizarre story of the disgraced Labour minister (Macfadyen), John Stonehouse, who faked his own death in 1974, leaving his wife (Hawes) and children behind.
Having been married for 18 years sure adds authenticity to Hawes and Macfadyen's performances, with the Bodyguard star saying it was "a joy" to work with her husband again.
"We just had far too nice a time. There's this feeling of: 'They're married, how's this going to be?" Ultimately, he's an actor that I would have loved to work with anyway," Hawes told The Guardian.
"So yes, it was a joy."
The pair have previously shared the screen in spy drama Spooks between 2002 and 2004 and in 2007 black comedy Death at a Funeral, where they played husband and wife.
Written by John Preston, Stonehouse follows the titular politician, a rising star in the Labour party who was later revealed to be a spy for the Czech Secret Service. In November 1974, Stonehouse left a pile of clothes on a beach in Miami to make it look like he had drowned. In fact, he was going to start to a new life in Australia with his secretary and mistress Sheila Buckley.
Stonehouse used a new alias after faking his own death, but his ruse only lasted a month before the Australian authorities arrested him, though believing he was a different fugitive.
"What happened to John Stonehouse is the stuff of legend," Macfadyen said in February.
"I've always been intrigued by what motivated him to fake his own death, and leave behind the family he loved and doted upon and a promising political career."
Stonehouse is expected to air on ITV later in the year.
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