This year it is taking place today, Monday 15 July, and tomorrow, Tuesday 16 July.
The 48-hour online shopping event will see thousands of discounts on items across the Amazon website.
Shoppers can make huge savings on everything from technology and household gadgets to parenting and beauty supplies.
Today’s ‘deals of the day’ include everything from a De'Longhi Eletta Cappuccino Maker to brighten up your morning to a Canon Digital SLR Camera.
We’ve rounded up all the best deals to shop below.
How do you take part?
You have to be an Amazon Prime member in order to take part in the event.
Already a member? Great – go on and shop your heart out.
If you’re not yet a member, you can still cash in on the annual savings day by signing up for the Amazon Prime 30-day free trial - which gives you exclusive access to Prime Day savings.
The editors at Yahoo UK are committed to finding you the best products at the best prices. At times, we may receive a share from purchases made via links on this page. These prices were correct at the time of publication.