What happened Shares of rare-disease specialist Vertex Pharmaceuticals (NASDAQ: VRTX) fell by as much as 15.7% in pre-market trading Thursday morning. The biotech's stock is under pressure today due to a worrying safety signal observed in a midstage trial for the small-molecule drug VX-814 as a potential treatment for alpha-1 antitrypsin deficiency (AATD).
Many people have been left impressed after finding out about the 'little known' function they never knew existed
Stephanie Langley said ‘I’m glad I did it’ as paramedics tried to save him, court told
Israel’s strike on Iran on Friday morning will not come as a surprise to Western observers – but it will cause great concern in Washington and London as the region tips closer towards an all-out war.
Samantha Davis, the wife of Star Wars and Harry Potter actor Warwick Davis and herself an actress, has died aged 53. Samantha co-founded the dwarfism charity Little People UK and featured in the final Harry Potter film, alongside Warwick. Warwick announced the news in a statement to the BBC, revealing she had died on 24 March.
Concerns have been raised that people have no idea of a massive post Brexit change which could lead to delays at airports
Following the Cass Review, a riveting ding-dong has broken out on X (formerly Twitter) between JK Rowling and the TV presenter Kirstie Allsopp. In broad terms, Allsopp belongs to the Pollyannaish “Be kind to trans people” (what harm do pronouns do?) side.
The rock legend appeared live on the show with Ben and Cat Deeley to celebrate and reflect on his 40-year career with his band
The bank has issued a warning to its customers, with the 21 to 40 age group making up nearly half of all reported cases
King Charles is said to have extended an olive branch to his youngest son and his wife by 'hinting' they should visit Balmoral this summer - but it could put the couple in a 'difficult position'.
Meghan Markle was on hand to congratulate her husband Prince Harry and his Royal Salute Sentebale team after they won the Royal Salute Polo Cup in Wellington, Florida
Victoria Beckham marked her 50th birthday on Wednesday and her rarely-seen sister shared a fabulous photo of her Spice Girl sister. See photo.
Springtime On The Farm returned to Channel 5 with Helen Skelton and Jules Hudson but fans had the same complaint for the show and the former Blue Peter presenter
Speed limits could be dramatically changed in one part of the UK from next week as opposition politicians demand an immediate review amid a growing resentment of 20mph zones
The Duke of Sussex has made a change on official documents
The supermarket is urging customers to return the product for a full refund
The dancer confirmed the news to fans ahead of the BBC One dance contest returning later this year
The soap star has issued a heartfelt tribute
The rest of Europe, Remainers like to tell us, is forging ahead into a glorious green future while Brexit Britain is stalling, the government backsliding one by one on its net zero commitments.
The Duke and Duchess of Edinburgh's daughter Lady Louise Windsor has to follow a very antiquated rule with regards to her younger brother James, Earl of Wessex
The Lemme co-founder is thankful for her body because it "gave me my 3 big babies and my little baby"
