The nurse has claimed the lives of Leanna Cavanagh and Andrea Tate in recent months, and we know she was also involved in the death of her friend Nadine.
Now the question is: who will Meena’s next victim be? Could one of the villagers meet their maker during the festive season?
Read more: Next week on Emmerdale
With plenty of characters already on her radar, here’s a look at Meena’s potential hit list.
She’s already tried to end Victoria’s (Isabel Hodgins) life once, but will Meena bide her time and make another attempt? After all, she’s definitely not over the other woman’s betrayal with ex-beau David Metcalfe.
Meena doesn’t let go of her grudges, so Victoria could certainly be at risk this winter...
In Meena’s eyes, she’s wasted months of her life with David (Matthew Wolfenden) only to lose him to Victoria. Could she decide that if she can’t have him, no one can?
There’s no one else in the village Meena has invested so much time in, so even if she does accept that he doesn’t love her, it’s possible Meena could snap and end David’s life.
When Jacob (Joe-Warren Plant) urged her to leave his family alone, Meena unnerved him with a thinly-veiled threat.
If she refuses to move on from David, could Jacob have another run-in with Meena and see her true colours? If so, he could find himself in mortal peril.
Looking out for best friend Victoria, Amy (Natalie Ann Jamieson) once again warns Meena to back off in upcoming scenes.
While Amy isn’t scared of Meena, she really should be. If their feud escalates, Meena might just decide to bump Amy off rather than deal with her inconvenient presence.
Billy (Jay Kontzle) will step in to help Meena during her confrontation with Amy, and she is thrilled with the gesture. Is he about to become her new obsession?
But if Billy doesn’t respond to Meena’s advances in the way she wants, could she see red and fatally attack him?
Meena may be about to set her sights on Billy, but he’s still got unfinished business with ex-girlfriend Dawn (Olivia Bromley).
It’s been hinted that Billy and Dawn could grow closer in the lead up to Christmas - so if Meena sees her as a threat, could Dawn be her latest victim?
He doesn’t know it yet, but Ben’s (Simon Lennon) camera footage from the ill-fated adventure week caught Meena deliberately holding injured Victoria under water.
Surely it’s only a matter of time before he reviews the recording again - and if Meena finds out what he knows, she’ll have no hesitation in silencing him forever.
Grieving Liam (Jonny McPherson) is about to face his first Christmas without beloved late daughter Leanna. He has no idea that the person responsible for his unbearable loss has been playing the supportive friend.
Meena’s flippant attitude has been more transparent lately, and Liam is an intelligent man. If he picks up on her suspicious behaviour, Meena may decide it’s time he joined Leanna...
After being seriously injured in the fire, Priya (Fiona Wade) was just waking up from sedation when Meena wandered into her hospital room.
Concerned that Priya’s story would cast doubt over her version of events, Meena prepared to kill her - but was interrupted. Could Priya recall this incident and recognise hearing Meena’s voice, leaving her in danger?
If there’s one character whose life Meena might spare, surely it’s big sister Manpreet (Rebecca Sarker). But the respectable doctor is the person closest to her, and so might be best placed to get to the truth.
Might Meena feel ‘forced’ into murdering Manpreet?
Let’s face it, it would be foolish to rule it out.
Emmerdale airs every night on ITV. Watch the latest spoilers below.