The charity spin-off of Channel 4's hit TV contest will return on Sunday, 19 March at 7.45pm with 20 famous amateur bakers showing their kitchen skills to judges Prue Leith and Paul Hollywood.
Along with Friends star Schwimmer, Towie's Collins and Olympic diver Daley, the cast will include TV presenter AJ Odudu, The Repair Shop's Jay Blades, and ex-Little Mix star Jesy Nelson.
Comedian and Loose Woman Judi Love will join them, as will Dragons' Den's Deborah Meaden, Ted Lasso and Strictly star Ellie Taylor, TV presenter and comedian Paddy McGuinness, and radio DJ Adele Roberts.
Also headed for the tent are actors Rose Matafeo, Jessica Hynes, David Morrissey and Tom Davis.
Completing the cast for the 2023 competition are another Loose Women star Coleen Nolan, comedians Lucy Beaumont and Mike Wozniak, Inbetweeners star Joe Thomas and poet Tim Key.
Each episode will see four celebrities compete in the signature bake, technical challenge and showstopper rounds, with one of them crowned Star Baker at the end of each episode.
In December, presenter Lucas announced he would be stepping down from his presenting role on the main show as he could no longer commit to the programme's schedule alongside his other projects.
Schwimmer, best known for playing Ross Geller in Friends, said he joined the charity special to "raise more awareness" about cancer.
He said: "I lost a grandmother to cancer, my daughter lost a grandmother to cancer and my sister is a cancer survivor, so it’s important to me.
"I am just grateful I can help in any small way to raise more awareness.
"I am here to have fun. I am here to raise money for a great charity. It's a great cause and I happen to be a massive fan of the show."
Singer Ellie Goulding and presenter Emma Willis were among the stars who were crowned Star Baker last year in the charity series.
Stand Up To Cancer, launched in 2012, is a joint national fundraising campaign from Cancer Research UK and Channel 4 with more than £93 million raised in the UK to date.
The Great British Bake Off 2022 was won by Syabira Yusoff, a 32-year-old cardiovascular research assistant from Malaysia.
Celebrity Bake Off full line-up
With a new Celebrity Bake Off comes a new batch of would-be baking hopefuls. Here are all of the big names taking part in this year's charity special.
David Schwimmer, Friends star
Tom Davis, comedian
Rose Matafeo, comedian
Jesy Nelson, ex-Little Mix singer
Jay Blades MBE, The Repair Shop star
Judi Love, Loose Women star
Mike Wozniak, comedian
Deborah Meaden, Dragons' Den star
Ellie Taylor, comedian
Gemma Collins, Towie star
Tim Key, poet
AJ Odudu, presenter
Jessica Hynes, actor
Paddy McGuinness, presenter
Coleen Nolan, Loose Women star
Joe Thomas, The Inbetweeners star
Tom Daley OBE, Olympian
David Morrissey, actor
Lucy Beaumont, comedian
Adele Roberts, Radio 1 DJ
Watch: 2023 Celebrity Bake Off lineup revealed