The breakfast news host has been absent from the ITV show since a nasty footballing accident that left him in need of surgery, but two weeks after the operation he is back on air.
As co-host Susanna Reid opened the show on Monday, she said: "Hello stranger! Welcome back!
"You look slightly uncomfortable - I'm just going to get the mini cam."
Reid panned to the view from under the Good Morning Britain desk, where Shephard was sitting with his injured leg propped up on a stool in an awkward-looking pose.
Explaining to viewers what had happened, Shephard, 46, said: "If you're not aware, and I've done my best to try and tell as many people as possible, my right leg here, I've ruptured the ACL and tore the meniscus and did various other things trying to pretend I'm still only a 25-year-old - sadly, I'm not.
"I've had an operation to repair it all."
Shephard added that Good Morning Britain's resident medic Dr Hilary had helped him to make sense of his footballing injury by explaining that the ACL connected the top and bottom parts of the leg.
Dr Hilary joked: "I love it when patients start using medical jargon - ACL - like they're an expert."
Shephard also shared his social media updates of the view from his hospital bed before and after his operation, where Good Morning Britain could be seen playing on the TV in his room as he waited for surgery.
Reid told him: "I'm glad to see you still watch us."
Shephard replied: "I couldn't get out of bed to change the channel."
But despite their jokes, Shephard's co-stars were clearly pleased to have him in work again as Reid told him: "It's really good to have you back."
Watch: Ben Shephard makes 'uncomfortable' return to Good Morning Britain